There are many different types of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) therapies available, but what do they all mean? PRP is a therapy that uses blood plasma with high levels of platelets. Platelets are important for healing damaged tissue. PRF is similar to PRP, but it also includes the fibrin protein. This helps the platelets stay together and form clots. Both PRP and PRF therapies have been shown to be effective in healing injuries and promoting cell growth. Now you are asking yourself, which one is right for you?


There is a lot of buzz around PRP treatment, but what is it? PRP is a medical grade treatment that uses your own blood to help heal injured tissue. By using your own platelets rich in growth factors and injecting them into a specific location on the body, healing is concentrated and precise. This allows your body to heal and rejuvenate skin to lessen fine lines and wrinkles and minimize the effects of sun damaged skin. It can also be used to promote hair growth where there is hair loss or thinning.

PRP treatment is a non-surgical procedure that uses platelet rich plasma to help regenerate tissue and improve the appearance of scars, sun damaged skin, wrinkles and even reverse hair loss. Mixed with anticoagulants to keep the platelets suspended until in the body, you get maximum benefit from the platelets. Platelets are activated once injected, not before. The medical grade PRP uses three and a half times more platelets than traditional ‘test tube’ PRP and is 95% more effective.

Usually, the PRP is injected into the dermis but can also be injected deeper into the skin or used as a topical agent. This makes PRP an appealing option for those looking to improve the appearance of blemishes or rejuvenate aging skin. Results are significantly more noticeable with PRP than PRF and last longer.


PRF is a similar treatment and often used to help with fine lines and wrinkles. It is also injected into the skin, but it creates a controlled inflammatory response. PRF also uses growth factors and platelet cytokines. This helps start new cell growth in skin and hair and collagen production.

PRF is not mixed with anticoagulants so the platelets are often already activated when injected into the patient. The fibrin is what activates the platelets in the absence of anticoagulants. When platelets are activated the growth factors kick in, which in turn promote healing and creating new cells. Because the platelet activation takes place on contact with the fibrin, there is less platelet activation in the body. There is a small diminished result compared to the PRP.

The Best Option

PRF is a safe procedure for you, however the results may not be to the full extent you are expecting. Dr. Yaplee is certified and experienced in PRP procedures. The medical grade PRP Triangle Eye uses offers 3 times more platelets on average than the PRF. The higher quality plasma helps with your long-term results.

PRP may not be as common as PRF due to the medical grade features, but it works more efficiently to reduce fine lines and wrinkles and improve the overall appearance of skin. PRP gives significantly more dramatic anti-aging results.

If you are considering PRP or PRF for your fine lines or wrinkles, or just to improve skin tone and blemishes, be sure to contact Triangle Eye Institute. We offer a variety of treatments, including PRP, and procedures to improve the health and appearance of your skin. Dr. Yaplee and our team of experts will work with you to develop a treatment plan that meets your needs and goals.